Wednesday 9 January 2013

The Role Of Fluorine Within The Pharmaceutical Industry

In general, most people associate the ninth element on the periodic table, fluorine, with dentistry. However, this is only one side of this versatile chemical. In its pure form, it is definitely a poisonous gas, unfit for consumption by humans. Many derivatives regarding the element are harmless or even beneficial to body. In fact, medicines containing fluorine are extremely common.



It is estimated that nearly 20% of all pharmaceuticals contain some sort of fluorine. This is due to the fact that the chemical is highly versatile. Slight changes in atomic structure can drastically change the nature of this element. For medicines, the intended result of a change in structure is an organofluorine compound. Those that work to develop pharmaceuticals are constantly working to make new varieties of these substances and location them in drugs.



There exists a many common Fluorine-containing compounds that are frequently used in health related technology. Treatments that contain this element are used in dentistry, anesthesiology, hormone therapy, oncology, and psychology. Sodium Fluoride Sodium fluoride is created creating use of the byproducts regarding the synthesis of chemical fertilizers and other products for agriculture. The manufacturing process of these products gives off hydrofluoric acid that is neutralized and becomes NaF. Most uses of this compound involve cleaning or organic synthesis.



The use of sodium fluoride in medicine is mostly within the realm of dentistry. It is located in many tooth pastes and other anti-tooth decay products. At one time, NaF was added to most drinking h2o sequential to improve oral well-being within the general population. It has generally been replaced by another fluorine compound, in part, due to the fact that the practice is very controversial. Sodium fluoride is moral for oral well-being purposes due to the fact that it creates a byproduct called fluoroapatite.



This compound is a component of tooth enamel, and, when coupled with the compound's ability to sleek most solid surfaces, helps to maintain well teeth. Anesthesia The general anesthesia used to place patients to sleep during surgery is usually created up of highly flammable gases. Fluorine is so well-known within the field of health related science due to the fact that it should be used in a variations of situations. The properties of this element make it easy to synthesize with other chemicals. It is known for its stability and reactivity.



Many of its greatest attributes should be applied to other substances by joining them together. Fluorocarbons are particularly stable and hold an above polarity. This creates them moral for use with the volatile chemicals used in anesthesia. They significantly reduce the flammability regarding the gasses used within the operating room, and therefore, make the process safer. Antidepressants The products of fluorine are often used to treat clinical depression and are classified as SSRIs.



Selective serotonin reuptake inhibitors change the chemical environment within the brain. Different chemicals released and detected by neurotransmitters send and receive chemical messages that determine mood. Serotonin is one regarding the chemical messengers that evoke a feeling of wellness. Since depression is likely the result of a challenge within the detection of serotonin, different drugs are synthesized to hold the chemical within the synapses longer. Unfortunately, though there is enough evidence of success to continue studies in this vein, these drugs are highly controversial.



Many charge that researchers are trying to manipulate brain chemistry without fully understanding it. Fluoxetine is component regarding the compound that created up Prozac, one regarding first SSRI drugs. It is approved as an antidepressant by the FDA and still in circulation, but it, as many similar medicines, was accused of encouraging suicide, insomnia, and sexual dysfunction. Other Uses Some antibiotics employ to fluoro-structures sequential to distant stabilize the compound. Fluoroquinolones are a huge team of broad-spectrum antibiotics.



They can be particularly affective in killing bacteria. Some fluorides are even used as cutting edge treatments for HIV. There exists a slew of other specialty drugs that contain some variation of fluorine. It is notably component of some antifungal drugs and steroids. Creating use of fluoride was a trend in technological health related studies for some time, but new uses for the element appear everyday.



Importance of Fluorine The fact that a derivative of fluorine should be located in one fifth of all pharmaceuticals speaks to its general importance. 67% of Americans ingest sodium chloride everyday in their drinking water. The versatility and stability of these substances also allows them to make medicines in which they can be not the active ingredient more effective. As more studies is done within the health related field, this chemical continues to prove useful to fight illness. The universe of pharmaceuticals certainly should not be the similar to without it.

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